DNA Damage-Binding Protein 2 (DDB2) Antibody

Catalogue No: abx001528
Price: £120.00
(Size: 20 µl)
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DNA Damage-Binding Protein 2 (DDB2) Antibody DNA Damage-Binding Protein 2 (DDB2) Antibody DNA Damage-Binding Protein 2 (DDB2) Antibody

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DDB2 Antibody is a Rabbit Polyclonal antibody against DDB2. This gene encodes a protein that is necessary for the repair of ultraviolet light-damaged DNA. This protein is the smaller subunit of a heterodimeric protein complex that participates in nucleotide excision repair, and this complex mediates the ubiquitylation of histones H3 and H4, which facilitates the cellular response to DNA damage. This subunit appears to be required for DNA binding. Mutations in this gene cause xeroderma pigmentosum complementation group E, a recessive disease that is characterized by an increased sensitivity to UV light and a high predisposition for skin cancer development, in some cases accompanied by neurological abnormalities. Two transcript variants encoding different isoforms have been found for this gene.

Target DDB2
Clonality Polyclonal
Reactivity Human, Mouse, Rat
Tested Applications WB, IF/ICC
Host Rabbit
Recommended dilutions WB: 1/500 - 1/2000, IF/ICC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Recombinant protein of human DDB2.
Isotype IgG
Form Liquid
Purification Affinity purified.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC Q92466 (UniProt, ExPASy)
UniProt Secondary AC B2R875, Q76E54, Q76E55, Q76E56, Q76E57
UniProt Entry Name DDB2_HUMAN
Gene Symbol DDB2
GeneID 1643
KEGG hsa:1643
String 9606.ENSP00000256996
Molecular Weight Calculated MW: 17 kDa, 26 kDa, 40 kDa, 47 kDa
Observed MW: 50 kDa
Buffer PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
Concentration > 1 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on DNA Damage-Binding Protein 2 (DDB2) Antibody

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