Aromatic-L-Amino-Acid Decarboxylase (DDC) Antibody

Catalogue No: abx002777
Price: £120.00
(Size: 20 µl)
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DDC Antibody is a Rabbit Polyclonal antibody against DDC. The encoded protein catalyzes the decarboxylation of L-3,4-dihydroxyphenylalanine (DOPA) to dopamine, L-5-hydroxytryptophan to serotonin and L-tryptophan to tryptamine. Defects in this gene are the cause of aromatic L-amino-acid decarboxylase deficiency (AADCD). AADCD deficiency is an inborn error in neurotransmitter metabolism that leads to combined serotonin and catecholamine deficiency. Multiple alternatively spliced transcript variants encoding different isoforms have been identified for this gene.

Target Aromatic-L-Amino-Acid Decarboxylase (DDC)
Clonality Polyclonal
Reactivity Human, Mouse, Rat
Tested Applications WB, IHC
Host Rabbit
Recommended dilutions WB: 1/200 - 1/2000, IHC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Recombinant protein of human DDC.
Isotype IgG
Form Liquid
Purification Purified by affinity chromatography.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC P20711 (UniProt, ExPASy)
UniProt Secondary AC C9IYA0, E7ER62, E7EU95, Q16723, Q5W5T9, Q75MJ6
UniProt Entry Name DDC_HUMAN
Gene Symbol DDC
GeneID 1644
KEGG hsa:1644
String 9606.ENSP00000403644
Molecular Weight Calculated MW: 37 kDa, 44 kDa, 45 kDa, 53 kDa
Observed MW: 54 kDa
Buffer PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
Concentration > 0.5 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on Aromatic-L-Amino-Acid Decarboxylase (DDC)

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