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DNA Damage Inducible Transcript 3 (DDIT3) Antibody

Catalogue No: abx000607
Price: £120.00
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DDIT3 Antibody is a Rabbit Polyclonal antibody against DDIT3. This gene encodes a member of the CCAAT/enhancer-binding protein (C/EBP) family of transcription factors. The protein functions as a dominant-negative inhibitor by forming heterodimers with other C/EBP members, such as C/EBP and LAP (liver activator protein), and preventing their DNA binding activity. The protein is implicated in adipogenesis and erythropoiesis, is activated by endoplasmic reticulum stress, and promotes apoptosis. Fusion of this gene and FUS on chromosome 16 or EWSR1 on chromosome 22 induced by translocation generates chimeric proteins in myxoid liposarcomas or Ewing sarcoma. Multiple alternatively spliced transcript variants encoding two isoforms with different length have been identified.

Target DDIT3
Clonality Polyclonal
Reactivity Human, Mouse, Rat
Tested Applications WB
Host Rabbit
Recommended dilutions WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Recombinant protein of human DDIT3.
Isotype IgG
Form Liquid
Purification Affinity purified.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC P35638 (UniProt, ExPASy)
UniProt Secondary AC F8VS99
UniProt Entry Name DDIT3_HUMAN
Gene Symbol DDIT3
GeneID 1649
String 9606.ENSP00000448665
Molecular Weight Calculated MW: 19 kDa, 21 kDa
Observed MW: 26 kDa
Buffer PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
Concentration > 1 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on DNA Damage Inducible Transcript 3 (DDIT3) Antibody

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