DEAD-Box Helicase 20 (DDX20) Antibody

DDX20 Antibody is a Rabbit Polyclonal antibody against DDX20. DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein, which has an ATPase activity and is a component of the survival of motor neurons (SMN) complex. This protein interacts directly with SMN, the spinal muscular atrophy gene product, and may play a catalytic role in the function of the SMN complex on RNPs.

Target	DEAD-Box Helicase 20 (DDX20)
Clonality	Polyclonal
Reactivity	Human, Mouse, Rat
Tested Applications	WB, IF/ICC
Host	Rabbit
Recommended dilutions	WB: 1/500 - 1/2000, IF/ICC: 1/10 - 1/100. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 25-280 of human DDX20.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	Q9UHI6 (UniProt, ExPASy)
UniProt Secondary AC	B4DWV7, Q96F72, Q9NVM3, Q9UF59, Q9UIY0, Q9Y659
UniProt Entry Name	DDX20_HUMAN
Gene Symbol	DDX20
GeneID	11218
NCBI Accession	NP_009135.4
String	9606.ENSP00000358716
Molecular Weight	Calculated MW: 92 kDa Observed MW: 110 kDa
Buffer	PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol.
Concentration	> 0.2 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on DEAD-Box Helicase 20 (DDX20)

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