DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 21 (DDX21) Antibody
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Catalogue No: abx029380
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US$326.25
(Size: 80 µl)
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Datasheet SDS
DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein, which is an antigen recognized by autoimmune antibodies from a patient with watermelon stomach disease. This protein unwinds double-stranded RNA, folds single-stranded RNA, and may play important roles in ribosomal RNA biogenesis, RNA editing, RNA transport, and general transcription.
Research Articles on DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 21 (DDX21)
| Target | DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 21 (DDX21) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 128-156 amino acids from the N-terminal region of human DDX21. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at 2-8°C for up to 2 weeks, or at -20°C for long term storage. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | Q9NR30 (UniProt, ExPASy) |
| UniProt Secondary AC | B2RDL0, Q13436, Q5VX41, Q68D35 |
| UniProt Entry Name | DDX21_HUMAN |
| Gene Symbol | DDX21 |
| String | 9606.ENSP00000346120 |
| Molecular Weight | Calculated MW: 87.3 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |