DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 46 (DDX46) Antibody

DDX46 Antibody is a Rabbit Polyclonal antibody against DDX46. This gene encodes a member of the DEAD box protein family. DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure, such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. The protein encoded by this gene is a component of the 17S U2 snRNP complex; it plays an important role in pre-mRNA splicing. Multiple alternatively spliced transcript variants have been found for this gene.

Target	DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 46 (DDX46)
Clonality	Polyclonal
Reactivity	Human, Mouse, Rat
Tested Applications	WB, IHC
Host	Rabbit
Recommended dilutions	WB: 1/500 - 1/1000, IHC-P: 1/50 - 1/100. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 682-1031 of human DDX46.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	Q7L014 (UniProt, ExPASy)
UniProt Secondary AC	O94894, Q96EI0, Q9Y658
UniProt Entry Name	DDX46_HUMAN
GeneID	9879
NCBI Accession	NP_055644.2
KEGG	hsa:9879
String	9606.ENSP00000416534
Molecular Weight	Calculated MW: 117 kDa Observed MW: 117 kDa
Buffer	PBS, pH 7.3, containing 0.01% thimerosal, 50% glycerol.
Concentration	> 0.2 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 46 (DDX46)

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