Beta-Defensin 132 (DEFB132) Antibody

DEFB132 Antibody is a Rabbit Polyclonal antibody against DEFB132. ∫-defensins (also designated BDs, or hBDs in human) are small cationic peptides with broad-spectrum antimicrobial activity against a variety of enveloped viruses, fungi and bacteria. Produced in mucosal epithelia and neutrophils of several species, ∫-defensins are developmentally regulated. The family of ∫-defensin proteins share a common defensin-motif that is characterized by multiple cysteine residues and a highly conserved tertiary structure. Besides playing a significant role in host immune defense, many ∫-defensins also are involved in sperm maturation and capacitation. ∫-defensin 32, also known as ∫-defensin 132, is a 95 amino acid secreted protein that most likely contains a signal peptide sequence that requires cleavage by proteolytic enzymes in order to become biologically active.

Target	Beta-Defensin 132 (DEFB132)
Clonality	Polyclonal
Reactivity	Mouse
Tested Applications	WB
Host	Rabbit
Recommended dilutions	WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 1-95 of human DEFB132.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	Q7Z7B7 (UniProt, ExPASy)
UniProt Secondary AC	B2RP72, Q4QY40
UniProt Entry Name	DB132_HUMAN
Gene Symbol	DEFB132
GeneID	400830
NCBI Accession	NP_997352.1
KEGG	hsa:400830
String	9606.ENSP00000371813
Molecular Weight	Calculated MW: 11 kDa Observed MW: 13 kDa
Buffer	PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol.
Concentration	> 0.2 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Beta-Defensin 132 (DEFB132)

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