Dihydrofolate Reductase (DHFR) Antibody

Catalogue No: abx001351
Price: £120.00
(Size: 20 µl)
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Dihydrofolate Reductase (DHFR) Antibody

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DHFR Antibody is a Rabbit Polyclonal antibody against DHFR. Dihydrofolate reductase converts dihydrofolate into tetrahydrofolate, a methyl group shuttle required for the de novo synthesis of purines, thymidylic acid, and certain amino acids. While the functional dihydrofolate reductase gene has been mapped to chromosome 5, multiple intronless processed pseudogenes or dihydrofolate reductase-like genes have been identified on separate chromosomes. Dihydrofolate reductase deficiency has been linked to megaloblastic anemia. [provided by RefSeq, Jul 2008].

Target DHFR
Clonality Polyclonal
Reactivity Human, Mouse
Tested Applications WB, IF/ICC
Host Rabbit
Recommended dilutions WB: 1/500 - 1/2000, IF/ICC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Recombinant protein of human DHFR.
Isotype IgG
Form Liquid
Purification Affinity purified.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC P00374 (UniProt, ExPASy)
UniProt Secondary AC B4DDD2, Q14130, Q6IRW8
UniProt Entry Name DYR_HUMAN
Gene Symbol DHFR
GeneID 1719
KEGG hsa:1719
String 9606.ENSP00000396308
Molecular Weight Calculated MW: 15 kDa, 21 kDa
Observed MW: 19 kDa
Buffer PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
Concentration > 1 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on Dihydrofolate Reductase (DHFR) Antibody

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