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DIABLO Antibody is a Rabbit Polyclonal antibody against DIABLO. This gene encodes an inhibitor of apoptosis protein (IAP)-binding protein. The encoded mitochondrial protein enters the cytosol when cells undergo apoptosis, and allows activation of caspases by binding to inhibitor of apoptosis proteins. Overexpression of the encoded protein sensitizes tumor cells to apoptosis. A mutation in this gene is associated with young-adult onset of nonsyndromic deafness-64. Alternative splicing results in multiple transcript variants encoding different isoforms.
| Target |
DIABLO |
| Clonality |
Polyclonal |
| Reactivity |
Human, Mouse |
| Tested Applications |
WB |
| Host |
Rabbit |
| Recommended dilutions |
WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation |
Unconjugated |
| Immunogen |
Recombinant protein of human DIABLO. |
| Isotype |
IgG |
| Form |
Liquid |
| Purification |
Affinity purified. |
| Storage |
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC |
Q9NR28 (UniProt,
ExPASy)
|
| UniProt Secondary AC |
B2RDQ0, Q6W3F3, Q96LV0, Q9BT11, Q9HAV6 |
| UniProt Entry Name |
DBLOH_HUMAN |
| Gene Symbol |
DIABLO |
| GeneID |
56616
|
| String |
9606.ENSP00000398495
|
| Molecular Weight |
Calculated MW: 21 kDa, 22 kDa, 27 kDa
Observed MW: 18 kDa |
| Buffer |
PBS, pH 7.3, 0.02% sodium azide, 50% glycerol. |
| Concentration |
> 1 mg/ml |
| Availability |
Shipped within 5-10 working days. |
| Note |
This product is for research use only. |
Research Articles on Second Mitochondria-Derived Activator of Caspase / SMAC (DIABLO) Antibody
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