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Second Mitochondria-Derived Activator of Caspase / SMAC (DIABLO) Antibody

Catalogue No: abx002001
Price: £120.00
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Second Mitochondria-Derived Activator of Caspase / SMAC (DIABLO) Antibody

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DIABLO Antibody is a Rabbit Polyclonal antibody against DIABLO. This gene encodes an inhibitor of apoptosis protein (IAP)-binding protein. The encoded mitochondrial protein enters the cytosol when cells undergo apoptosis, and allows activation of caspases by binding to inhibitor of apoptosis proteins. Overexpression of the encoded protein sensitizes tumor cells to apoptosis. A mutation in this gene is associated with young-adult onset of nonsyndromic deafness-64. Alternative splicing results in multiple transcript variants encoding different isoforms.

Target DIABLO
Clonality Polyclonal
Reactivity Human, Mouse
Tested Applications WB
Host Rabbit
Recommended dilutions WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Recombinant protein of human DIABLO.
Isotype IgG
Form Liquid
Purification Affinity purified.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC Q9NR28 (UniProt, ExPASy)
UniProt Secondary AC B2RDQ0, Q6W3F3, Q96LV0, Q9BT11, Q9HAV6
UniProt Entry Name DBLOH_HUMAN
Gene Symbol DIABLO
GeneID 56616
String 9606.ENSP00000398495
Molecular Weight Calculated MW: 21 kDa, 22 kDa, 27 kDa
Observed MW: 18 kDa
Buffer PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
Concentration > 1 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on Second Mitochondria-Derived Activator of Caspase / SMAC (DIABLO) Antibody

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