Dicer 1, Ribonuclease Type III (DICER1) Antibody

DICER1 Antibody is a Rabbit Monoclonal antibody against DICER1. This gene encodes a protein possessing an RNA helicase motif containing a DEXH box in its amino terminus and an RNA motif in the carboxy terminus. The encoded protein functions as a ribonuclease and is required by the RNA interference and small temporal RNA (stRNA) pathways to produce the active small RNA component that represses gene expression. Alternative splicing results in multiple transcript variants.

Target	Dicer 1, Ribonuclease Type III (DICER1)
Clonality	Monoclonal
Reactivity	Human, Mouse, Rat
Tested Applications	WB, IHC, IF/ICC, IP
Host	Rabbit
Recommended dilutions	WB: 1/500 - 1/1000, IHC-P: 1/50 - 1/200, IF/ICC: 1/100 - 1/200, IP: 0.5-4 µg/200-400 µg whole cell extracts. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 1200-1460 of human DICER1.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	Q9UPY3 (UniProt, ExPASy)
UniProt Secondary AC	A7E2D3, B3KRG4, E0AD28, O95943, Q9UQ02
UniProt Entry Name	DICER_HUMAN
Gene Symbol	DICER1
GeneID	23405
NCBI Accession	NP_085124.2
String	9606.ENSP00000437256
Molecular Weight	Calculated MW: 219 kDa Observed MW: 250 kDa
Buffer	PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol.
Concentration	0.363 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Dicer 1, Ribonuclease Type III (DICER1)

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