Dimethyl-Histone H3-K14 Antibody
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Catalogue No: abx000035
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US$232.00
(Size: 20 µl)
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Datasheet SDS
Dimethyl-Histone H3-K14 Antibody is a Rabbit Polyclonal antibody against Dimethyl-Histone H3-K14. Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a member of the histone H3 family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is located separately from the other H3 genes that are in the histone gene cluster on chromosome 6p22-p21.3.
Research Articles on Dimethyl-Histone H3-K14
| Target | Dimethyl-Histone H3-K14 |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | ELISA, WB, IF/ICC |
| Host | Rabbit |
| Recommended dilutions | ELISA: 1 µg/ml, WB: 1/500 - 1/1000, IF/ICC: 1/20 - 1/50. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | A synthetic monomethylated peptide around K14 of human MonoMethyl-Histone H3-K14. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | Q16695 (UniProt, ExPASy) |
| UniProt Secondary AC | B2R5K3, Q6FGU4 |
| UniProt Entry Name | H31T_HUMAN |
| Gene Symbol | HIST3H3 |
| GeneID | 8290 |
| NCBI Accession | NP_003520.1 |
| KEGG | hsa:8290 |
| String | 9606.ENSP00000355657 |
| Molecular Weight | Calculated MW: 16 kDa Observed MW: 17 kDa |
| Buffer | PBS, pH 7.3, containing 0.01% thimerosal, 50% glycerol. |
| Concentration | > 0.2 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |