Disrupted In Schizophrenia 1 Protein (DISC1) Antibody

Catalogue No: abx002129
Price: £120.00
(Size: 20 µl)
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DISC1 Antibody is a Rabbit Polyclonal antibody against DISC1. This gene encodes a protein with multiple coiled coil motifs which is located in the nucleus, cytoplasm and mitochondria. The protein is involved in neurite outgrowth and cortical development through its interaction with other proteins. This gene is disrupted in a t(1;11)(q42.1;q14.3) translocation which segregates with schizophrenia and related psychiatric disorders in a large Scottish family. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Target DISC1
Clonality Polyclonal
Reactivity Human, Mouse, Rat
Tested Applications WB, IHC
Host Rabbit
Recommended dilutions WB: 1/500 - 1/2000, IHC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen A synthetic peptide of human DISC1.
Isotype IgG
Form Liquid
Purification Affinity purified.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC Q9NRI5 (UniProt, ExPASy)
UniProt Entry Name DISC1_HUMAN
Gene Symbol DISC1
GeneID 27185
String 9606.ENSP00000355593
Molecular Weight Calculated MW: 22 kDa, 37-38 kDa, 6-93 kDa
Observed MW: 105 kDa
Buffer PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
Concentration > 1 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on Disrupted In Schizophrenia 1 Protein (DISC1) Antibody

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