Disrupted In Schizophrenia 1 Protein (DISC1) Antibody

DISC1 Antibody is a Rabbit Polyclonal antibody against DISC1. This gene encodes a protein with multiple coiled coil motifs which is located in the nucleus, cytoplasm and mitochondria. The protein is involved in neurite outgrowth and cortical development through its interaction with other proteins. This gene is disrupted in a t(1;11)(q42.1;q14.3) translocation which segregates with schizophrenia and related psychiatric disorders in a large Scottish family. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Target	Disrupted In Schizophrenia 1 Protein (DISC1)
Clonality	Polyclonal
Reactivity	Human, Mouse, Rat
Tested Applications	WB
Host	Rabbit
Recommended dilutions	WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 1-200 of human DISC1.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	Q9NRI5 (UniProt, ExPASy)
UniProt Entry Name	DISC1_HUMAN
Gene Symbol	DISC1
GeneID	27185
NCBI Accession	NP_001158009.1
String	9606.ENSP00000355593
Molecular Weight	Calculated MW: 94 kDa Observed MW: 105 kDa
Buffer	PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol.
Concentration	> 0.2 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Disrupted In Schizophrenia 1 Protein (DISC1)

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