DLC1 Antibody is a Rabbit Polyclonal antibody against DLC1. This gene encodes a GTPase-activating protein (GAP) that is a member of the rhoGAP family of proteins which play a role in the regulation of small GTP-binding proteins. GAP family proteins participate in signaling pathways that regulate cell processes involved in cytoskeletal changes. This gene functions as a tumor suppressor gene in a number of common cancers, including prostate, lung, colorectal, and breast cancers. Multiple transcript variants due to alternative promoters and alternative splicing have been found for this gene.
| Target |
DLC1 |
| Clonality |
Polyclonal |
| Reactivity |
Mouse, Rat |
| Tested Applications |
WB, IHC |
| Host |
Rabbit |
| Recommended dilutions |
WB: 1/500 - 1/2000, IHC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation |
Unconjugated |
| Immunogen |
Recombinant protein of human DLC1. |
| Isotype |
IgG |
| Form |
Liquid |
| Purification |
Affinity purified. |
| Storage |
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC |
Q96QB1 (UniProt,
ExPASy)
|
| UniProt Entry Name |
RHG07_HUMAN |
| Gene Symbol |
DLC1 |
| GeneID |
10395
|
| KEGG |
hsa:10395
|
| String |
9606.ENSP00000276297
|
| Molecular Weight |
Calculated MW: 50 kDa, 54 kDa, 114 kDa, 122 kDa, 126 kDa, 170 kDa
Observed MW: 176 kDa |
| Buffer |
PBS, pH 7.3, 0.02% sodium azide, 50% glycerol. |
| Concentration |
> 1 mg/ml |
| Availability |
Shipped within 5-10 working days. |
| Note |
This product is for research use only. |
Research Articles on Rho GTPase-Activating Protein 7 (DLC1) Antibody
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