DnaJ Homolog Subfamily C Member 2 (DNAJC2) Antibody

DNAJC2 Antibody is a Rabbit Polyclonal antibody against DNAJC2. This gene is a member of the M-phase phosphoprotein (MPP) family. The gene encodes a phosphoprotein with a J domain and a Myb DNA-binding domain which localizes to both the nucleus and the cytosol. The protein is capable of forming a heterodimeric complex that associates with ribosomes, acting as a molecular chaperone for nascent polypeptide chains as they exit the ribosome. This protein was identified as a leukemia-associated antigen and expression of the gene is upregulated in leukemic blasts. Also, chromosomal aberrations involving this gene are associated with primary head and neck squamous cell tumors. This gene has a pseudogene on chromosome 6. Alternatively spliced variants which encode different protein isoforms have been described.

Target	DnaJ Homolog Subfamily C Member 2 (DNAJC2)
Clonality	Polyclonal
Reactivity	Human, Mouse
Tested Applications	WB
Host	Rabbit
Recommended dilutions	WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 1-140 of human DNAJC2.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	Q99543 (UniProt, ExPASy)
UniProt Secondary AC	A4VCI0, Q9BVX1
UniProt Entry Name	DNJC2_HUMAN
Gene Symbol	DNAJC2
GeneID	27000
NCBI Accession	NP_055192.1
KEGG	hsa:27000
String	9606.ENSP00000368565
Molecular Weight	Calculated MW: 72 kDa Observed MW: 80/72 kDa
Buffer	PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol.
Concentration	> 0.2 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on DnaJ Homolog Subfamily C Member 2 (DNAJC2)

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