DNase I

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Catalogue No: abx082222
Price: US$217.50
(Size: 100 mg)

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Datasheet SDS
DNase I is an enzyme isolated from Cow pancreas.
  • Appearance: White to faint yellow to faint brown powder
  • Loss on drying: ≤ 5.0%
  • Density: 100 g/ml at 20°C

DNase I (also known as Deoxyribonuclease I), is an endonuclease of the DNase family coded for by the DNASE1 gene. DNase I is a nuclease that cleaves DNA at phosphodiester linkages that are adjacent to a pyrimidine nucleotide, yielding 5'-phosphate-terminated polynucleotides with a free hydroxyl group on position 3', usually producing tetranucleotides. It acts on single and double-stranded DNA and chromatin. It is also one of the deoxyribonucleases responsible for DNA fragmentation during apoptosis.

Target DNase I
Origin Cow
Expression Native
Host Cow
Conjugation Unconjugated
Form Lyophilized
Biological Activity ≥ 2000 Kunitz units/mg protein
One Kunitz unit will produce a change in A260 of 0.001 per minute per ml at pH 5.0 at 25°C, using DNA Type I or III as the substrate.
Storage Store at -20°C. Avoid repeated freeze/thaw cycles.
Shelf Life 12 months.
Buffer Not applicable.
CAS Number 9003-98-9
Availability Shipped within 5-10 working days.
Note THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION.
Research Articles on DNase I


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