Dynamin-2 (DNM2) Antibody
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Catalogue No: abx000741
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US$348.00
(Size: 60 µl)
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Datasheet SDS
DNM2 Antibody is a Rabbit Polyclonal antibody against DNM2. Dynamins represent one of the subfamilies of GTP-binding proteins. These proteins share considerable sequence similarity over the N-terminal portion of the molecule, which contains the GTPase domain. Dynamins are associated with microtubules. They have been implicated in cell processes such as endocytosis and cell motility, and in alterations of the membrane that accompany certain activities such as bone resorption by osteoclasts. Dynamins bind many proteins that bind actin and other cytoskeletal proteins. Dynamins can also self-assemble, a process that stimulates GTPase activity. Five alternatively spliced transcripts encoding different proteins have been described. Additional alternatively spliced transcripts may exist, but their full-length nature has not been determined.
Research Articles on Dynamin-2 (DNM2)
| Target | Dynamin-2 (DNM2) |
| Research Area | Metabolism, Developmental Science, Bone Metabolism |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | WB, IF/ICC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/500 - 1/2000, IF/ICC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | A synthetic peptide corresponding to human DNM2 |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | P50570 (UniProt, ExPASy) |
| UniProt Secondary AC | A8K1B6, E7EV30, E9PEQ4, K7ESI9, Q5I0Y0, Q7Z5S3, Q9UPH4 |
| UniProt Entry Name | DYN2_HUMAN |
| Gene Symbol | DNM2 |
| GeneID | 1785 |
| NCBI Accession | NP_004936.2 |
| KEGG | hsa:1785 |
| String | 9606.ENSP00000373905 |
| Molecular Weight | Calculated MW: 97 kDa/98 kDa Observed MW: 110 kDa |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Concentration | 1 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
