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DNA Methyltransferase 3 Alpha (DNMT3A) Antibody
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Catalogue No: abx001682
Price:
US$348.00
(Size: 60 µl)
Orders to United States ship from United States
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DNMT3A Antibody is a Rabbit Polyclonal antibody against DNMT3A. CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a DNA methyltransferase that is thought to function in de novo methylation, rather than maintenance methylation. The protein localizes to the cytoplasm and nucleus and its expression is developmentally regulated. Alternative splicing results in multiple transcript variants encoding different isoforms.
Research Articles on DNA Methyltransferase 3 Alpha (DNMT3A)
| Target | DNA Methyltransferase 3 Alpha (DNMT3A) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant fusion protein corresponding to human DNMT3A |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | Q9Y6K1 (UniProt, ExPASy) |
| UniProt Secondary AC | E9PEB8, Q86TE8, Q86XF5, Q8IZV0, Q8WXU9 |
| UniProt Entry Name | DNM3A_HUMAN |
| Gene Symbol | DNMT3A |
| GeneID | 1788 |
| NCBI Accession | NP_072046.2 |
| String | 9606.ENSP00000264709 |
| Molecular Weight | Calculated MW: 16 kDa/81 kDa/101 kDa Observed MW: 110 kDa/130 kDa |
| Buffer | PBS, pH 7.3, containing 0.01% thiomersal, 50% glycerol. |
| Concentration | 1 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
