DNA Methyltransferase 3 Alpha (DNMT3A) Antibody

Catalogue No: abx001682
Price: £120.00
(Size: 20 µl)
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DNA Methyltransferase 3 Alpha (DNMT3A) Antibody DNA Methyltransferase 3 Alpha (DNMT3A) Antibody

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DNMT3A Antibody is a Rabbit Polyclonal antibody against DNMT3A. CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a DNA methyltransferase that is thought to function in de novo methylation, rather than maintenance methylation. The protein localizes to the cytoplasm and nucleus and its expression is developmentally regulated. Alternative splicing results in multiple transcript variants encoding different isoforms.

Target DNMT3A
Clonality Polyclonal
Reactivity Human, Mouse
Tested Applications WB, IF/ICC
Host Rabbit
Recommended dilutions WB: 1/500 - 1/2000, IF/ICC: 1/20 - 1/100. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Recombinant protein of human DNMT3A.
Isotype IgG
Form Liquid
Purification Affinity purified.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC Q9Y6K1 (UniProt, ExPASy)
UniProt Secondary AC E9PEB8, Q86TE8, Q86XF5, Q8IZV0, Q8WXU9
UniProt Entry Name DNM3A_HUMAN
Gene Symbol DNMT3A
GeneID 1788
String 9606.ENSP00000264709
Molecular Weight Calculated MW: 16 kDa, 81 kDa, 101 kDa
Observed MW: 110 kDa
Buffer PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
Concentration > 1 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on DNA Methyltransferase 3 Alpha (DNMT3A) Antibody

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