DNA (cytosine-5)-Methyltransferase 3A (DNMT3A) Antibody

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Catalogue No: abx025649
Price: US$326.25
(Size: 80 µl)

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Datasheet SDS
CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. DNMT3A is a DNA methyltransferase that is thought to function in de novo methylation, rather than maintenance methylation. The protein localizes to the cytoplasm and nucleus and its expression is developmentally regulated.

Target DNA (cytosine-5)-Methyltransferase 3A (DNMT3A)
Clonality Polyclonal
Reactivity Human
Tested Applications ELISA, WB
Host Rabbit
Recommended dilutions WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen KLH-conjugated synthetic peptide between 723-752 amino acids from the C-terminal region of human Dnmt3A/Dnmt3A2.
Isotype IgG
Form Liquid
Purification Purified through a protein A column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC Q9Y6K1 (UniProt, ExPASy)
UniProt Secondary AC E9PEB8, Q86TE8, Q86XF5, Q8IZV0, Q8WXU9
UniProt Entry Name DNM3A_HUMAN
NCBI Accession NP_072046.2 NP_715640.2 NP_783328.1 NP_783329.1
String 9606.ENSP00000264709
Molecular Weight Calculated MW: 102 kDa
Buffer PBS containing 0.09% sodium azide.
Specificity Predicted to react with Mouse and Rat DNMT3A.
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on DNA (cytosine-5)-Methyltransferase 3A (DNMT3A)


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