Menu

DNA Methyltransferase 3 Like (DNMT3L) Antibody

Catalogue No: abx001899
Price: £120.00
Reviews: 0 reviews
(0 reviews)

Click on the image to see the image legend

DNA Methyltransferase 3 Like (DNMT3L) Antibody

Available Options

* Size:




DNMT3L Antibody is a Rabbit Polyclonal antibody against DNMT3L. CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a nuclear protein with similarity to DNA methyltransferases, but is not thought to function as a DNA methyltransferase as it does not contain the amino acid residues necessary for methyltransferase activity. However, it does stimulate de novo methylation by DNA cytosine methyltransferase 3 alpha and is thought to be required for the establishment of maternal genomic imprints. This protein also mediates transcriptional repression through interaction with histone deacetylase 1. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Target DNMT3L
Clonality Polyclonal
Reactivity Human
Tested Applications IF/ICC
Host Rabbit
Recommended dilutions IF/ICC: 1/20 - 1/50. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Recombinant protein of human DNMT3L.
Isotype IgG
Form Liquid
Purification Affinity purified.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC Q9UJW3 (UniProt, ExPASy)
UniProt Secondary AC E9PB42, Q9BUJ4
UniProt Entry Name DNM3L_HUMAN
Gene Symbol DNMT3L
GeneID 29947
String 9606.ENSP00000270172
Molecular Weight Calculated MW: 43 kDa
Buffer PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
Concentration > 1 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on DNA Methyltransferase 3 Like (DNMT3L) Antibody

Write a review

Your Name
Your Email Address
PMID
DOI
Type
Your Review

Note: HTML is not translated!

Rating Bad Good