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DOK2 (pY299) Antibody
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Catalogue No: abx000302
Price:
US$377.00
(Size: 50 µl)
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DOK2 (pY299) Antibody is a Rabbit Polyclonal antibody against DOK2 (pY299). The protein encoded by this gene is constitutively tyrosine phosphorylated in hematopoietic progenitors isolated from chronic myelogenous leukemia (CML) patients in the chronic phase. It may be a critical substrate for p210(bcr/abl), a chimeric protein whose presence is associated with CML. This encoded protein binds p120 (RasGAP) from CML cells.
Research Articles on DOK2 (pY299)
| Target | DOK2 (pY299) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | WB, IF/ICC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/500 - 1/2000, IF/ICC: 1/100 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | A phospho specific peptide corresponding to residues surrounding Y299 of human DOK2 |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | O60496 (UniProt, ExPASy) |
| UniProt Secondary AC | Q8N5A4 |
| UniProt Entry Name | DOK2_HUMAN |
| Gene Symbol | DOK2 |
| GeneID | 9046 |
| KEGG | hsa:9046 |
| String | 9606.ENSP00000276420 |
| Molecular Weight | Calculated MW: 45 kDa Observed MW: 55 kDa |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Concentration | > 0.2 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |
