Diphthamide Biosynthesis Protein 2 (DPH2) Antibody

This gene is one of two human genes similar to the yeast gene dph2. The yeast gene was identified by its ability to complement a diphthamide mutant strain, and thus probably functions in diphthamide biosynthesis. Diphthamide is a post-translationally modified histidine residue present in elongation factor 2 (EF2) that is the target of diphtheria toxin ADP-ribosylation. Two transcript variants encoding different isoforms have been found for this gene.

Target	Diphthamide Biosynthesis Protein 2 (DPH2)
Clonality	Polyclonal
Reactivity	Human
Tested Applications	ELISA, WB
Host	Rabbit
Recommended dilutions	WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	KLH-conjugated synthetic peptide between 121-148 amino acids from the N-terminal region of human DPH2.
Isotype	IgG
Form	Liquid
Purification	Purified through a protein A column, followed by peptide affinity purification.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	Q9BQC3 (UniProt, ExPASy)
UniProt Secondary AC	A8MVC9, B2RDE3, B4DNI8, O60623
UniProt Entry Name	DPH2_HUMAN
Gene Symbol	DPH2
String	9606.ENSP00000255108
Molecular Weight	Calculated MW: 52.1 kDa
Buffer	PBS containing 0.09% sodium azide.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Diphthamide Biosynthesis Protein 2 (DPH2)

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