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Dihydropyrimidine Dehydrogenase (DPYD) Antibody

Catalogue No: abx001364
Price: £120.00
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Dihydropyrimidine Dehydrogenase (DPYD) Antibody

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DPYD Antibody is a Rabbit Polyclonal antibody against DPYD. The protein encoded by this gene is a pyrimidine catabolic enzyme and the initial and rate-limiting factor in the pathway of uracil and thymidine catabolism. Mutations in this gene result in dihydropyrimidine dehydrogenase deficiency, an error in pyrimidine metabolism associated with thymine-uraciluria and an increased risk of toxicity in cancer patients receiving 5-fluorouracil chemotherapy. Two transcript variants encoding different isoforms have been found for this gene.

Target DPYD
Clonality Polyclonal
Reactivity Human, Mouse
Tested Applications WB
Host Rabbit
Recommended dilutions WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Recombinant protein of human DPYD.
Isotype IgG
Form Liquid
Purification Affinity purified.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC Q12882 (UniProt, ExPASy)
UniProt Entry Name DPYD_HUMAN
Gene Symbol DPYD
GeneID 1806
KEGG hsa:1806
String 9606.ENSP00000359211
Molecular Weight Calculated MW: 18 kDa, 111 kDa
Observed MW: 110 kDa
Buffer PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
Concentration > 1 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on Dihydropyrimidine Dehydrogenase (DPYD) Antibody

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