Dopamine Receptor D2 (DRD2) Antibody

This gene encodes the D2 subtype of the dopamine receptor. This G-protein coupled receptor inhibits adenylyl cyclase activity. A missense mutation in this gene causes myoclonus dystonia; other mutations have been associated with schizophrenia. Alternative splicing of this gene results in two transcript variants encoding different isoforms. A third variant has been described, but it has not been determined whether this form is normal or due to aberrant splicing.

Target	Dopamine Receptor D2 (DRD2)
Clonality	Polyclonal
Reactivity	Human
Tested Applications	ELISA, WB
Host	Rabbit
Recommended dilutions	WB: 1/2000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	KLH-conjugated synthetic peptide between 307-336 amino acids from the C-terminal region of human DRD2.
Isotype	IgG
Form	Liquid
Purification	Purified through a protein A column, followed by peptide affinity purification.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P14416 (UniProt, ExPASy)
UniProt Secondary AC	Q9NZR3, Q9UPA9
UniProt Entry Name	DRD2_HUMAN
Gene Symbol	DRD2
GeneID	1813
OMIM	103780
HGNC	3023
KEGG	hsa:1813
Ensembl	ENSG00000149295
String	9606.ENSP00000354859
Molecular Weight	Calculated MW: 50.6 kDa
Buffer	PBS containing 0.09% sodium azide.
Specificity	Predicted to react with Mouse DRD2.
Concentration	0.5 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Dopamine Receptor D2 (DRD2)

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