Dopamine Receptor D3 (DRD3) Antibody

DRD3 Antibody is a Rabbit Polyclonal antibody against DRD3. This gene encodes the D3 subtype of the five (D1-D5) dopamine receptors. The activity of the D3 subtype receptor is mediated by G proteins which inhibit adenylyl cyclase. This receptor is localized to the limbic areas of the brain, which are associated with cognitive, emotional, and endocrine functions. Genetic variation in this gene may be associated with susceptibility to hereditary essential tremor 1. Alternative splicing of this gene results in transcript variants encoding different isoforms, although some variants may be subject to nonsense-mediated decay (NMD).

Target	Dopamine Receptor D3 (DRD3)
Clonality	Polyclonal
Reactivity	Human, Mouse, Rat
Tested Applications	WB, IF/ICC
Host	Rabbit
Recommended dilutions	WB: 1/500 - 1/2000, IF/ICC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 213-329 of human Dopamine Receptor D3 (DRD3).
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P35462 (UniProt, ExPASy)
UniProt Secondary AC	A1A4V5, Q4VBM8
UniProt Entry Name	DRD3_HUMAN
Gene Symbol	DRD3
GeneID	1814
NCBI Accession	NP_000787.2
KEGG	hsa:1814
String	9606.ENSP00000373169
Molecular Weight	Calculated MW: 44 kDa Observed MW: 44 kDa
Buffer	PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol.
Concentration	> 0.2 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Dopamine Receptor D3 (DRD3)

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