Desmoglein 3 (DSG3) Antibody
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Catalogue No: abx028219
Price:
US$326.25
(Size: 80 µl)
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Datasheet SDS
Desmosomes are cell-cell junctions between epithelial, myocardial, and certain other cell types. Desmoglein 3 is a calcium-binding transmembrane glycoprotein component of desmosomes in vertebrate epithelial cells. Currently, three desmoglein subfamily members have been identified and all are members of the cadherin cell adhesion molecule superfamily. These desmoglein gene family members are located in a cluster on chromosome 18. This protein has been identified as the autoantigen of the autoimmune skin blistering disease pemphigus vulgaris.
Research Articles on Desmoglein 3 (DSG3)
| Target | Desmoglein 3 (DSG3) |
| Research Area | Cellular Differentiation and Adhesion, Infection Immunity |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 8-36 amino acids from the N-terminal region of human DSG3. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at 2-8°C for up to 2 weeks, or at -20°C for long term storage. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | P32926 (UniProt, ExPASy) |
| UniProt Secondary AC | A8K2V2 |
| UniProt Entry Name | DSG3_HUMAN |
| Gene Symbol | DSG3 |
| KEGG | hsa:1830 |
| String | 9606.ENSP00000257189 |
| Molecular Weight | Calculated MW: 108 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |