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Dual Specificity Phosphatase 4 (DUSP4) Antibody

Catalogue No: abx002069
Price: £120.00
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Dual Specificity Phosphatase 4 (DUSP4) Antibody

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DUSP4 Antibody is a Rabbit Polyclonal antibody against DUSP4. The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which are associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product inactivates ERK1, ERK2 and JNK, is expressed in a variety of tissues, and is localized in the nucleus. Two alternatively spliced transcript variants, encoding distinct isoforms, have been observed for this gene. In addition, multiple polyadenylation sites have been reported.

Target DUSP4
Clonality Polyclonal
Reactivity Human, Monkey
Tested Applications WB
Host Rabbit
Recommended dilutions WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Recombinant protein of human DUSP4.
Isotype IgG
Form Liquid
Purification Affinity purified.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC Q13115 (UniProt, ExPASy)
UniProt Secondary AC B2RBU5, D3DSU4, G5E930, Q13524
UniProt Entry Name DUS4_HUMAN
Gene Symbol DUSP4
GeneID 1846
KEGG hsa:1846
String 9606.ENSP00000240100
Molecular Weight Calculated MW: 32 kDa, 42 kDa
Observed MW: 43 kDa
Buffer PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
Concentration > 1 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on Dual Specificity Phosphatase 4 (DUSP4) Antibody

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