Dynein Light Chain 1, Cytoplasmic (DYNLL1) Antibody
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Catalogue No: abx004392
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US$348.00
(Size: 60 µl)
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Datasheet SDS
DYNLL1 Antibody is a Rabbit Polyclonal antibody against DYNLL1. Cytoplasmic dyneins are large enzyme complexes with a molecular mass of about 1,200 kD. They contain two force-producing heads formed primarily from dynein heavy chains, and stalks linking the heads to a basal domain, which contains a varying number of accessory intermediate chains. The complex is involved in intracellular transport and motility. The protein described in this record is a light chain and exists as part of this complex but also physically interacts with and inhibits the activity of neuronal nitric oxide synthase. Binding of this protein destabilizes the neuronal nitric oxide synthase dimer, a conformation necessary for activity, and it may regulate numerous biologic processes through its effects on nitric oxide synthase activity. Alternate transcriptional splice variants have been characterized.
Research Articles on Dynein Light Chain 1, Cytoplasmic (DYNLL1)
| Target | Dynein Light Chain 1, Cytoplasmic (DYNLL1) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | A synthetic peptide corresponding to human DYNLL1 |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | P63167 (UniProt, ExPASy) |
| UniProt Secondary AC | Q15701 |
| UniProt Entry Name | DYL1_HUMAN |
| Gene Symbol | DYNLL1 |
| GeneID | 8655 |
| NCBI Accession | NP_003737.1 |
| KEGG | hsa:8655 |
| String | 9606.ENSP00000376297 |
| Molecular Weight | Calculated MW: 10 kDa Observed MW: 12 kDa |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Concentration | 1 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
