Dynein Light Chain Tctex-Type 1 (DYNLT1) Antibody

Catalogue No: abx003064
Price: £120.00
(Size: 20 µl)
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DYNLT1 Antibody is a Rabbit Polyclonal antibody against DYNLT1. This gene encodes a component of the motor complex, cytoplasmic dynein, which transports cellular cargo along microtubules in the cell. The encoded protein regulates the length of primary cilia which are sensory organelles found on the surface of cells. The protein encoded by this gene interacts with viral proteins, like the minor capsid protein L2 of human papillomavirus, and is required for dynein-mediated delivery of the viral nucleic acid to the host nucleus. This protein interacts with oncogenic nucleoporins to disrupt gene regulation and cause leukemic transformation. Pseudogenes of this gene are present on chromosomes 4 and 17. Alternative splicing results in multiple transcript variants encoding different isoforms.

Target DYNLT1
Clonality Polyclonal
Reactivity Human, Mouse
Tested Applications WB
Host Rabbit
Recommended dilutions WB: 1/200 - 1/2000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Recombinant protein of human DYNLT1.
Isotype IgG
Form Liquid
Purification Purified by affinity chromatography.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC P63172 (UniProt, ExPASy)
UniProt Secondary AC Q15763, Q5VTU4
UniProt Entry Name DYLT1_HUMAN
Gene Symbol DYNLT1
GeneID 6993
KEGG hsa:6993
String 9606.ENSP00000356056
Molecular Weight Calculated MW: 12 kDa
Observed MW: 13 kDa
Buffer PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
Concentration > 0.5 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on DYNLT1

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