Dynein Light Chain Tctex-Type 1 (DYNLT1) Antibody

DYNLT1 Antibody is a Rabbit Polyclonal antibody against DYNLT1. This gene encodes a component of the motor complex, cytoplasmic dynein, which transports cellular cargo along microtubules in the cell. The encoded protein regulates the length of primary cilia which are sensory organelles found on the surface of cells. The protein encoded by this gene interacts with viral proteins, like the minor capsid protein L2 of human papillomavirus, and is required for dynein-mediated delivery of the viral nucleic acid to the host nucleus. This protein interacts with oncogenic nucleoporins to disrupt gene regulation and cause leukemic transformation. Pseudogenes of this gene are present on chromosomes 4 and 17. Alternative splicing results in multiple transcript variants encoding different isoforms.

Target	Dynein Light Chain Tctex-Type 1 (DYNLT1)
Clonality	Polyclonal
Reactivity	Human, Mouse
Tested Applications	WB
Host	Rabbit
Recommended dilutions	WB: 1/200 - 1/2000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 1-113 of human DYNLT1.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P63172 (UniProt, ExPASy)
UniProt Secondary AC	Q15763, Q5VTU4
UniProt Entry Name	DYLT1_HUMAN
Gene Symbol	DYNLT1
GeneID	6993
NCBI Accession	NP_006510.1
KEGG	hsa:6993
String	9606.ENSP00000356056
Molecular Weight	Calculated MW: 12 kDa Observed MW: 13 kDa
Buffer	PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol.
Concentration	> 0.2 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Dynein Light Chain Tctex-Type 1 (DYNLT1)

Write a review

Your Name

Your Email Address

PMID

DOI

Your Review

Rating

Continue