Dual Specificity Tyrosine-Phosphorylation-Regulated Kinase 2 (DYRK2) Antibody

DYRK2 Antibody is a Rabbit Polyclonal antibody against DYRK2. DYRK2 belongs to a family of protein kinases whose members are presumed to be involved in cellular growth and/or development. The family is defined by structural similarity of their kinase domains and their capability to autophosphorylate on tyrosine residues. DYRK2 has demonstrated tyrosine autophosphorylation and catalyzed phosphorylation of histones H3 and H2B in vitro. Two isoforms of DYRK2 have been isolated. The predominant isoform, isoform 1, lacks a 5' terminal insert.

Target	Dual Specificity Tyrosine-Phosphorylation-Regulated Kinase 2 (DYRK2)
Clonality	Polyclonal
Reactivity	Human, Mouse
Tested Applications	WB, IF/ICC
Host	Rabbit
Recommended dilutions	WB: 1/500 - 1/1000, IF/ICC: 1/20 - 1/100. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 429-528 of human DYRK2.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	Q92630 (UniProt, ExPASy)
UniProt Secondary AC	B2R9V9, Q9BRB5
UniProt Entry Name	DYRK2_HUMAN
Gene Symbol	DYRK2
GeneID	8445
NCBI Accession	NP_003574.1
KEGG	hsa:8445
String	9606.ENSP00000342105
Molecular Weight	Calculated MW: 67 kDa Observed MW: 67 kDa
Buffer	PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol.
Concentration	> 0.2 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Dual Specificity Tyrosine-Phosphorylation-Regulated Kinase 2 (DYRK2)

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