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E3 Ubiquitin-Protein Ligase RING1 (RING1) Antibody
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Catalogue No: abx015978
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US$427.75
(Size: 100 µl)
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Datasheet SDS
This gene belongs to the RING finger family, members of which encode proteins characterized by a RING domain, a zinc-binding motif related to the zinc finger domain.The gene product can bind DNA and can act as a transcriptional repressor.It is associated with the multimeric polycomb group protein complex.The gene product interacts with the polycomb group proteins BMI1, EDR1, and CBX4, and colocalizes with these proteins in large nuclear domains.It interacts with the CBX4 protein via its glycine-rich C-terminal domain.The gene maps to the HLA class II region, where it is contiguous with the RING finger genes FABGL and HKE4.
Research Articles on E3 Ubiquitin-Protein Ligase RING1 (RING1)
| Target | E3 Ubiquitin-Protein Ligase RING1 (RING1) |
| Clonality | Monoclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB, IHC, FCM |
| Host | Mouse |
| Recommended dilutions | ELISA: 1/10000, WB: 1/500 - 1/2000, IHC: 1/200 - 1/1000, FCM: 1/200 - 1/400. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Purified recombinant fragment of human Ring1 (AA: 79-263) expressed in E. coli. |
| Isotype | IgG1 |
| Form | Liquid |
| Purification | Purified from ascites by Protein G chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | Q06587 (UniProt, ExPASy) |
| UniProt Secondary AC | A8JZZ0, Q5JP96, Q5SQW2, Q86V19 |
| UniProt Entry Name | RING1_HUMAN |
| Gene Symbol | RING1 |
| GeneID | 6015 |
| OMIM | 602045 |
| HGNC | 10018 |
| KEGG | hsa:6015 |
| Ensembl | ENSG00000204227 |
| String | 9606.ENSP00000363787 |
| Molecular Weight | 42.4 kDa |
| Buffer | PBS, containing 0.05% sodium azide. |
| Concentration | 1 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |