Epithelial Cell Transforming Sequence 2 (ECT2) Antibody

The protein encoded by this gene is a transforming protein that is related to Rho-specific exchange factors and yeast cell cycle regulators. The expression of this gene is elevated with the onset of DNA synthesis and remains elevated during G2 and M phases. In situ hybridization analysis showed that expression is at a high level in cells undergoing mitosis in regenerating liver. Thus, this protein is expressed in a cell cycle-dependent manner during liver regeneration, and is thought to have an important role in the regulation of cytokinesis.

Target	Epithelial Cell Transforming Sequence 2 (ECT2)
Clonality	Polyclonal
Reactivity	Human
Tested Applications	ELISA, WB, IHC
Host	Rabbit
Recommended dilutions	WB: 1/1000, IHC-P: 1/10 - 1/50. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	KLH-conjugated synthetic peptide between 597-625 amino acids from the Central region of human ECT2.
Isotype	IgG
Form	Liquid
Purification	Purified through a protein A column, followed by peptide affinity purification.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	Q9H8V3 (UniProt, ExPASy)
UniProt Secondary AC	Q0MT80, Q2M269, Q6U836, Q9NSV8, Q9NVW9
UniProt Entry Name	ECT2_HUMAN
Gene Symbol	ECT2
String	9606.ENSP00000376457
Molecular Weight	Calculated MW: 104 kDa
Buffer	PBS containing 0.09% sodium azide.
Specificity	Predicted to react with Mouse ECT2.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Epithelial Cell Transforming Sequence 2 (ECT2)

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