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Ectonucleotide Pyrophosphatase/phosphodiesterase 2 (ENPP2) Antibody
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Catalogue No: abx240128
Price:
US$406.00
(Size: 100 µg)
Orders to United States ship from United States
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Ectonucleotide Pyrophosphatase/phosphodiesterase 2 (ENPP2) Antibody is a Rabbit Polyclonal antibody for the detection of Autotaxin. Hydrolyzes lysophospholipids to produce lysophosphatidic acid (LPA) in extracellular fluids. Major substrate is lysophosphatidylcholine. Also can act on sphingosylphosphphorylcholine producing sphingosine-1-phosphate, a modulator of cell motility. Can hydrolyze, in vitro, bis-pNPP, to some extent pNP-TMP, and barely ATP. Involved in several motility-related processes such as angiogenesis and neurite outgrowth. Acts as an angiogenic factor by stimulating migration of smooth muscle cells and microtubule formation. Stimulates migration of melanoma cells, probably via a pertussis toxin-sensitive G protein. May have a role in induction of parturition. Possible involvement in cell proliferation and adipose tissue development. Tumor cell motility-stimulating factor.
Research Articles on Ectonucleotide Pyrophosphatase/phosphodiesterase 2 (ENPP2)
| Target | Ectonucleotide Pyrophosphatase/phosphodiesterase 2 (ENPP2) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | ELISA, WB, IHC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/500 - 1/1000, IHC: 1/20 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | ectonucleotide pyrophosphatase/phosphodiesterase 2 |
| Isotype | IgG |
| Form | Liquid |
| Purity | ≥ 95% (SDS-PAGE) |
| Purification | Purified by immunogen affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Validity | 12 months. |
| UniProt Primary AC | Q13822 (UniProt, ExPASy) |
| UniProt Entry Name | ENPP2_HUMAN |
| Gene Symbol | ENPP2 |
| GeneID | 5168 |
| KEGG | hsa:5168 |
| String | 9606.ENSP00000259486 |
| Molecular Weight | Observed MW: 50 kDa, 60 kDa, 110-120 kDa |
| Buffer | PBS, pH 7.3, with 0.02% sodium azide and 50% glycerol. |
| Concentration | 2 mg/ml |
| Availability | Shipped within 5-12 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |