Tumor Necrosis Factor Receptor Superfamily Member 27 (EDA2R) Antibody
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Catalogue No: abx030265
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US$326.25
(Size: 80 µl)
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Datasheet SDS
EDA-A1 and EDA-A2 are two isoforms of ectodysplasin that are encoded by the anhidrotic ectodermal dysplasia (EDA) gene. Mutations in EDA give rise to a clinical syndrome characterized by loss of hair, sweat glands, and teeth. The protein encoded by this gene specifically binds to EDA-A2 isoform. This protein is a type III transmembrane protein of the TNFR (tumor necrosis factor receptor) superfamily, and contains 3 cysteine-rich repeats and a single transmembrane domain but lacks an N-terminal signal peptide. Multiple alternatively spliced transcript variants have been found for this gene, but some variants lack sufficient support. [provided by RefSeq].
Research Articles on Tumor Necrosis Factor Receptor Superfamily Member 27 (EDA2R)
| Target | Tumor Necrosis Factor Receptor Superfamily Member 27 (EDA2R) |
| Research Area | Ophthalmology and Otorhinolaryngology |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 267-297 amino acids from the C-terminal region of human EDA2R. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at 2-8°C for up to 2 weeks, or at -20°C for long term storage. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | Q9HAV5 (UniProt, ExPASy) |
| UniProt Secondary AC | Q5VYX9, Q5VYY0, Q6UWM2, Q8IZA6 |
| UniProt Entry Name | TNR27_HUMAN |
| Gene Symbol | EDA2R |
| String | 9606.ENSP00000379365 |
| Molecular Weight | Calculated MW: 32.8 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |