Ectodysplasin A Receptor (EDAR) Antibody

EDAR Antibody is a Rabbit Polyclonal antibody against EDAR. This gene encodes a member of the tumor necrosis factor receptor family. The encoded transmembrane protein is a receptor for the soluble ligand ectodysplasin A, and can activate the nuclear factor-kappaB, JNK, and caspase-independent cell death pathways. It is required for the development of hair, teeth, and other ectodermal derivatives. Mutations in this gene result in autosomal dominant and recessive forms of hypohidrotic ectodermal dysplasia.

Target	Ectodysplasin A Receptor (EDAR)
Clonality	Polyclonal
Reactivity	Human
Tested Applications	WB
Host	Rabbit
Recommended dilutions	WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 27-187 of human EDAR.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	Q9UNE0 (UniProt, ExPASy)
UniProt Secondary AC	B2R9H2, B4DLC5, D3DX74, E9PC98, Q52LL5, Q9UND9
UniProt Entry Name	EDAR_HUMAN
Gene Symbol	EDAR
GeneID	10913
NCBI Accession	NP_071731.1
String	9606.ENSP00000258443
Molecular Weight	Calculated MW: 49 kDa Observed MW: 48 kDa
Buffer	PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol.
Concentration	> 0.2 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Ectodysplasin A Receptor (EDAR)

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