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Endothelin 3 (EDN3) Antibody

Catalogue No: abx000972
Price: £120.00
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EDN3 Antibody is a Rabbit Polyclonal antibody against EDN3. The protein encoded by this gene is a member of the endothelin family. Endothelins are endothelium-derived vasoactive peptides involved in a variety of biological functions. The active form of this protein is a 21 amino acid peptide processed from the precursor protein. The active peptide is a ligand for endothelin receptor type B (EDNRB). The interaction of this endothelin with EDNRB is essential for development of neural crest-derived cell lineages, such as melanocytes and enteric neurons. Mutations in this gene and EDNRB have been associated with Hirschsprung disease (HSCR) and Waardenburg syndrome (WS), which are congenital disorders involving neural crest-derived cells. Four alternatively spliced transcript variants encoding three distinct isoforms have been observed. [provided by RefSeq, Jul 2008].

Target EDN3
Clonality Polyclonal
Reactivity Human
Tested Applications WB
Host Rabbit
Recommended dilutions WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Recombinant protein of human EDN3.
Isotype IgG
Form Liquid
Purification Affinity purified.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC P14138 (UniProt, ExPASy)
UniProt Secondary AC E1P5I5, Q03229, Q7Z6D2, Q9UGT7
UniProt Entry Name EDN3_HUMAN
Gene Symbol EDN3
GeneID 1908
KEGG hsa:190
String 9606.ENSP00000337128
Molecular Weight Calculated MW: 23 kDa, 25 kDa
Observed MW: 44 kDa
Buffer PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
Concentration > 1 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on Endothelin 3 (EDN3) Antibody

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