Endothelin Receptor Type B (EDNRB) Antibody
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Catalogue No: abx002134
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US$217.50
(Size: 20 µl)
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Datasheet SDS
EDNRB Antibody is a Rabbit Polyclonal antibody against EDNRB. The protein encoded by this gene is a G protein-coupled receptor which activates a phosphatidylinositol-calcium second messenger system. Its ligand, endothelin, consists of a family of three potent vasoactive peptides: ET1, ET2, and ET3. Studies suggest that the multigenic disorder, Hirschsprung disease type 2, is due to mutations in the endothelin receptor type B gene. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Research Articles on Endothelin Receptor Type B (EDNRB)
| Target | Endothelin Receptor Type B (EDNRB) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse |
| Tested Applications | ELISA, WB |
| Host | Rabbit |
| Recommended dilutions | ELISA: 1 µg/ml, WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant protein corresponding to EDNRB. The exact sequence is proprietary. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | P24530 (UniProt, ExPASy) |
| UniProt Entry Name | EDNRB_HUMAN |
| Gene Symbol | EDNRB |
| GeneID | 1910 |
| NCBI Accession | NP_001116131.1 |
| KEGG | hsa:1910 |
| String | 9606.ENSP00000366416 |
| Molecular Weight | Calculated MW: 50 kDa Observed MW: 49 kDa |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Concentration | > 0.2 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |