Embryonic Ectoderm Development (EED) Antibody

EED Antibody is a Rabbit Polyclonal antibody against EED. This gene encodes a member of the Polycomb-group (PcG) family. PcG family members form multimeric protein complexes, which are involved in maintaining the transcriptional repressive state of genes over successive cell generations. This protein interacts with enhancer of zeste 2, the cytoplasmic tail of integrin beta7, immunodeficiency virus type 1 (HIV-1) MA protein, and histone deacetylase proteins. This protein mediates repression of gene activity through histone deacetylation, and may act as a specific regulator of integrin function. Two transcript variants encoding distinct isoforms have been identified for this gene.

Target	Embryonic Ectoderm Development (EED)
Clonality	Polyclonal
Reactivity	Human, Mouse, Rat
Tested Applications	WB, IF/ICC, IP
Host	Rabbit
Recommended dilutions	WB: 1/500 - 1/2000, IP: 0.5-4 µg/200-400 µg whole cell extracts, IF/ICC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 1-400 of human EED.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	O75530 (UniProt, ExPASy)
UniProt Secondary AC	A8K7V5, O00149, Q6NTH2, Q7LDA5, Q7LDG8, Q86VV2, Q9UNY7
Gene Symbol	EED
GeneID	8726
NCBI Accession	NP_694536.1
Molecular Weight	Calculated MW: 50 kDa Observed MW: 50-70 kDa
Buffer	PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol.
Concentration	1.92 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Embryonic Ectoderm Development (EED)

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