Pro-Epidermal Growth Factor (EGF) Antibody

EGF Antibody is a Rabbit Polyclonal antibody against EGF. This gene encodes a member of the epidermal growth factor superfamily. The encoded protein is synthesized as a large precursor molecule that is proteolytically cleaved to generate the 53-amino acid epidermal growth factor peptide. This protein acts a potent mitogenic factor that plays an important role in the growth, proliferation and differentiation of numerous cell types. This protein acts by binding the high affinity cell surface receptor, epidermal growth factor receptor. Defects in this gene are the cause of hypomagnesemia type 4. Dysregulation of this gene has been associated with the growth and progression of certain cancers. Alternate splicing results in multiple transcript variants.

Target	Pro-Epidermal Growth Factor (EGF)
Clonality	Polyclonal
Reactivity	Human, Mouse
Tested Applications	WB
Host	Rabbit
Recommended dilutions	DB: 1/500 - 1/2000, WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 971-1023 of human EGF.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P01133 (UniProt, ExPASy)
UniProt Secondary AC	B4DRK7, E7EVD2, E9PBF0, Q52LZ6
UniProt Entry Name	EGF_HUMAN
Gene Symbol	EGF
GeneID	1950
NCBI Accession	NP_001954.2
KEGG	hsa:1950
String	9606.ENSP00000265171
Molecular Weight	Calculated MW: 134 kDa Observed MW: 160 kDa
Buffer	PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol.
Concentration	> 0.2 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Pro-Epidermal Growth Factor (EGF)

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