EGFR mutant Antibody

Catalogue No: abx015844
Price: £290.00
(Size: 100 µl)

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Datasheet SDS
The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily.This protein is a receptor for members of the epidermal growth factor family.EGFR is a cell surface protein that binds to epidermal growth factor.Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation.Mutations in this gene are associated with lung cancer.Multiple alternatively spliced transcript variants that encode different protein isoforms have been found for this gene.

Target EGFR mutant
Clonality Monoclonal
Reactivity Human
Tested Applications ELISA, WB, IHC, FCM
Host Mouse
Recommended dilutions ELISA: 1/10000, WB: 1/500 - 1/2000, IHC: 1/200 - 1/1000, FCM: 1/200 - 1/400. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Purified recombinant fragment of human EGFR mutant (AA: 693-893) expressed in E. coli.
Isotype IgG1
Form Liquid
Purification Unpurified ascites.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC P00533 (UniProt, ExPASy)
UniProt Entry Name EGFR_HUMAN
Gene Symbol EGFR
GeneID 1956
OMIM 131550
HGNC 3236
KEGG hsa:1956
Ensembl ENSG00000146648
String 9606.ENSP00000275493
Molecular Weight 175 kDa
Buffer Ascitic fluid containing 0.03% sodium azide.
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on EGFR mutant

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