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Egl Nine Homolog 1 (EGLN1) Antibody

Catalogue No: abx001065
Price: £120.00
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EGLN1 Antibody is a Rabbit Polyclonal antibody against EGLN1. The protein encoded by this gene catalyzes the post-translational formation of 4-hydroxyproline in hypoxia-inducible factor (HIF) alpha proteins. HIF is a transcriptional complex that plays a central role in mammalian oxygen homeostasis. This protein functions as a cellular oxygen sensor, and under normal oxygen concentration, modification by prolyl hydroxylation is a key regulatory event that targets HIF subunits for proteasomal destruction via the von Hippel-Lindau ubiquitylation complex. Mutations in this gene are associated with erythrocytosis familial type 3 (ECYT3).

Target EGLN1
Clonality Polyclonal
Reactivity Human, Monkey
Tested Applications WB
Host Rabbit
Recommended dilutions WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Recombinant protein of human EGLN1.
Isotype IgG
Form Liquid
Purification Affinity purified.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC Q9GZT9 (UniProt, ExPASy)
UniProt Secondary AC Q8N3M8, Q9BZS8, Q9BZT0
UniProt Entry Name EGLN1_HUMAN
Gene Symbol EGLN1
GeneID 54583
String 9606.ENSP00000355601
Molecular Weight Calculated MW: 36 kDa, 43 kDa, 46 kDa
Observed MW: 45 kDa
Buffer PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
Concentration > 1 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on Egl Nine Homolog 1 (EGLN1) Antibody

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