EGLN2 Antibody

EGLN2 Antibody is a Rabbit Polyclonal antibody against EGLN2. The hypoxia inducible factor (HIF) is a transcriptional complex that is involved in oxygen homeostasis. At normal oxygen levels, the alpha subunit of HIF is targeted for degration by prolyl hydroxylation. This gene encodes an enzyme responsible for this post-translational modification. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the upstream RAB4B (RAB4B, member RAS oncogene family) gene.

Target	EGLN2
Clonality	Polyclonal
Reactivity	Human, Mouse, Rat
Tested Applications	WB, IP
Host	Rabbit
Recommended dilutions	WB: 1/500 - 1/2000, IP: 0.5-4 µg/200-400 µg whole cell extracts. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	A synthetic peptide corresponding to a sequence within amino acids 200-300 of human Prolyl hydroxylase PHD1 (EGLN2).
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	Q96KS0 (UniProt, ExPASy)
UniProt Secondary AC	A8K5S0, Q8WWY4, Q9BV14
UniProt Entry Name	EGLN2_HUMAN
Gene Symbol	EGLN2
GeneID	112398
NCBI Accession	NP_444274.1
KEGG	hsa:112398
String	9606.ENSP00000469686
Molecular Weight	Calculated MW: 44 kDa Observed MW: 43 kDa
Buffer	PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol.
Concentration	> 0.2 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on EGLN2

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