Euchromatic Histone-Lysine N-Methyltransferase 1 (EHMT1) Antibody
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Catalogue No: abx025627
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US$326.25
(Size: 80 µl)
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Datasheet SDS
EHMT1, also known as EUHMTASE1, is a histone methyltransferase. This protein methylates 'Lys-9' of histone H3 in vitro. H3 'Lys-9' methylation represents a specific tag for epigenetic transcriptional repression by recruiting HP1 proteins to methylated histones. EHMT1 is Probably targeted to histone H3 by different DNA-binding proteins like E2F6, MGA, MAX and/or DP1. During G0 phase, it probably contributes to silencing of MYC and E2F-responsive genes, suggesting a role in the G0/G1 transition of the cell cycle.
Research Articles on Euchromatic Histone-Lysine N-Methyltransferase 1 (EHMT1)
| Target | Euchromatic Histone-Lysine N-Methyltransferase 1 (EHMT1) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 203-233 amino acids from the N-terminal region of human EHMT1. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS. |
| Storage | Aliquot and store at 2-8°C for up to 2 weeks, or at -20°C for long term storage. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | Q9H9B1 (UniProt, ExPASy) |
| UniProt Secondary AC | B1AQ58, B1AQ59, Q86X08, Q8TCN7, Q96F53, Q96JF1, Q96KH4 |
| UniProt Entry Name | EHMT1_HUMAN |
| String | 9606.ENSP00000417980 |
| Molecular Weight | Calculated MW: 141 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |