Euchromatic Histone-Lysine N-Methyltransferase 1 (EHMT1) Antibody

EHMT1, also known as EUHMTASE1, is a histone methyltransferase. This protein methylates 'Lys-9' of histone H3 in vitro. H3 'Lys-9' methylation represents a specific tag for epigenetic transcriptional repression by recruiting HP1 proteins to methylated histones. EHMT1 is Probably targeted to histone H3 by different DNA-binding proteins like E2F6, MGA, MAX and/or DP1. During G0 phase, it probably contributes to silencing of MYC and E2F-responsive genes, suggesting a role in the G0/G1 transition of the cell cycle.

Target	Euchromatic Histone-Lysine N-Methyltransferase 1 (EHMT1)
Clonality	Polyclonal
Reactivity	Human
Tested Applications	ELISA, WB
Host	Rabbit
Recommended dilutions	WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	KLH-conjugated synthetic peptide between 203-233 amino acids from the N-terminal region of human EHMT1.
Isotype	IgG
Form	Liquid
Purification	Purified through a protein A column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	Q9H9B1 (UniProt, ExPASy)
UniProt Secondary AC	B1AQ58, B1AQ59, Q86X08, Q8TCN7, Q96F53, Q96JF1, Q96KH4
UniProt Entry Name	EHMT1_HUMAN
String	9606.ENSP00000417980
Molecular Weight	Calculated MW: 141 kDa
Buffer	PBS containing 0.09% sodium azide.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Euchromatic Histone-Lysine N-Methyltransferase 1 (EHMT1)

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