Eukaryotic Translation Initiation Factor 2 Alpha Kinase 3 (EIF2AK3) Antibody
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Catalogue No: abx011890
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US$427.75
(Size: 100 µl)
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Datasheet SDS
The protein encoded by this gene phosphorylates the alpha subunit of eukaryotic translation-initiation factor 2 (EIF2), leading to its inactivation, and thus to a rapid reduction of translational initiation and repression of global protein synthesis. It is a type I membrane protein located in the endoplasmic reticulum (ER), where it is induced by ER stress caused by malfolded proteins. Mutations in this gene are associated with Wolcott-Rallison syndrome.
Research Articles on Eukaryotic Translation Initiation Factor 2 Alpha Kinase 3 (EIF2AK3)
| Target | Eukaryotic Translation Initiation Factor 2 Alpha Kinase 3 (EIF2AK3) |
| Research Area | Developmental Science |
| Clonality | Monoclonal |
| Reactivity | Human |
| Tested Applications | ELISA |
| Host | Mouse |
| Recommended dilutions | ELISA: 1/10000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Purified recombinant fragment of human EIF2AK3 expressed in E. coli. |
| Isotype | IgG1 |
| Form | Liquid |
| Purification | Unpurified ascites. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | Q9NZJ5 (UniProt, ExPASy) |
| UniProt Secondary AC | A0AVH1, A0AVH2, B2RCU9, O95846, Q53QY0, Q53SB1 |
| UniProt Entry Name | E2AK3_HUMAN |
| Gene Symbol | EIF2AK3 |
| GeneID | 9451 |
| OMIM | 226980 |
| HGNC | 3255 |
| Ensembl | ENSG00000172071 |
| String | 9606.ENSP00000307235 |
| Enzyme Commission Number | EC 2.7.11.1 |
| Molecular Weight | 125 kDa |
| Buffer | Ascitic fluid containing 0.03% sodium azide. |
| Concentration | Not determined. |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |