Eukaryotic Translation Initiation Factor 2 Alpha Kinase 4 (EIF2AK4) Antibody

EIF2AK4 Antibody is a Rabbit Polyclonal antibody against EIF2AK4. This gene encodes a member of a family of kinases that phosphorylate the alpha subunit of eukaryotic translation initiation factor-2 (EIF2), resulting in the downregulaton of protein synthesis. The encoded protein responds to amino acid deprivation by binding uncharged transfer RNAs. It may also be activated by glucose deprivation and viral infection. Mutations in this gene have been found in individuals suffering from autosomal recessive pulmonary venoocclusive-disease-2.

Target	Eukaryotic Translation Initiation Factor 2 Alpha Kinase 4 (EIF2AK4)
Clonality	Polyclonal
Reactivity	Human, Mouse, Rat
Tested Applications	WB, IF/ICC
Host	Rabbit
Recommended dilutions	WB: 1/500 - 1/1000, IF/ICC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human GCN2.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	Q9P2K8 (UniProt, ExPASy)
UniProt Entry Name	E2AK4_HUMAN
Gene Symbol	EIF2AK4
GeneID	440275
NCBI Accession	NP_001013725.2
String	9606.ENSP00000263791
Molecular Weight	Calculated MW: 187 kDa Observed MW: 220 kDa
Buffer	PBS, pH 7.3, containing 0.05% Proclin-300, 50% glycerol.
Concentration	> 0.2 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Eukaryotic Translation Initiation Factor 2 Alpha Kinase 4 (EIF2AK4)

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