Eukaryotic Translation Initiation Factor 2 Subunit 1 (EIF2S1) Antibody

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Catalogue No: abx027407
Price: US$326.25
(Size: 80 µl)

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Datasheet SDS
The translation initiation factor EIF2 catalyzes the first regulated step of protein synthesis initiation, promoting the binding of the initiator tRNA to 40S ribosomal subunits. Binding occurs as a ternary complex of methionyl-tRNA, EIF2, and GTP. EIF2 is composed of 3 nonidentical subunits, the 36-kD EIF2-alpha subunit (EIF2S1), the 38-kD EIF2-beta subunit (EIF2S2; MIM 603908), and the 52-kD EIF2-gamma subunit (EIF2S3; MIM 300161). The rate of formation of the ternary complex is modulated by the phosphorylation state of EIF2-alpha (Ernst et al., 1987 [PubMed 2948954]).

Target Eukaryotic Translation Initiation Factor 2 Subunit 1 (EIF2S1)
Clonality Polyclonal
Reactivity Mouse
Tested Applications ELISA, WB, IHC, IF/ICC
Host Rabbit
Recommended dilutions WB: 1/1000, IHC-P: 1/10 - 1/50, IF/ICC: 1/10 - 1/50. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen KLH-conjugated synthetic peptide between 60-89 amino acids from the N-terminal region of human EIF2S1.
Isotype IgG
Form Liquid
Purification Purified through a protein A column, followed by peptide affinity purification.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC P05198 (UniProt, ExPASy)
UniProt Entry Name IF2A_HUMAN
KEGG hsa:1965
String 9606.ENSP00000256383
Molecular Weight Calculated MW: 36.1 kDa
Buffer PBS containing 0.09% sodium azide.
Specificity Predicted to react with Rat, Cow, Yeast, Zebrafish and Drosophila EIF2S1.
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on Eukaryotic Translation Initiation Factor 2 Subunit 1 (EIF2S1)


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