Eukaryotic Translation Initiation Factor 3 Subunit C (EIF3C) Antibody
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Catalogue No: abx028765
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US$326.25
(Size: 80 µl)
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Datasheet SDS
Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S preinitiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of posttermination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation.
Research Articles on Eukaryotic Translation Initiation Factor 3 Subunit C (EIF3C)
| Target | Eukaryotic Translation Initiation Factor 3 Subunit C (EIF3C) |
| Clonality | Polyclonal |
| Reactivity | Mouse |
| Tested Applications | ELISA, WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 538-566 amino acids from the Central region of human EIF3C. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at 2-8°C for up to 2 weeks, or at -20°C for long term storage. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | Q99613 (UniProt, ExPASy) |
| UniProt Secondary AC | A8K7Z0, B2RXG3, B4E1D5, H3BRV0, O00215, Q9BW98 |
| UniProt Entry Name | EIF3C_HUMAN |
| Gene Symbol | EIF3C |
| KEGG | hsa:8663 |
| String | 9606.ENSP00000332604 |
| Molecular Weight | Calculated MW: 105 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Specificity | Predicted to react with Human, Rat, Cow and Xenopus EIF3C. |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |