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EIF4EBP1 (pS65) Antibody

Catalogue No: abx000117
Price: £120.00
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EIF4EBP1 (pS65) Antibody

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EIF4EBP1 (pS65) Antibody is a Rabbit Polyclonal antibody against EIF4EBP1 (pS65). This gene encodes one member of a family of translation repressor proteins. The protein directly interacts with eukaryotic translation initiation factor 4E (eIF4E), which is a limiting component of the multisubunit complex that recruits 40S ribosomal subunits to the 5' end of mRNAs. Interaction of this protein with eIF4E inhibits complex assembly and represses translation. This protein is phosphorylated in response to various signals including UV irradiation and insulin signaling, resulting in its dissociation from eIF4E and activation of mRNA translation.

Target EIF4EBP1 (pS65)
Clonality Polyclonal
Reactivity Human, Mouse, Rat
Tested Applications WB
Host Rabbit
Recommended dilutions WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Synthetic Peptide. A phospho specific peptide corresponding to residues surrounding S65 of human EIF4EBP1.
Isotype IgG
Form Liquid
Purification Affinity purified.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC Q13541 (UniProt, ExPASy)
UniProt Secondary AC B2R502, D3DSW8, Q6IBN3
UniProt Entry Name 4EBP1_HUMAN
Gene Symbol EIF4EBP1
GeneID 1978
KEGG hsa:1978
String 9606.ENSP00000340691
Molecular Weight Calculated MW: 12 kDa
Observed MW: 18 kDa
Buffer PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
Concentration > 1 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on EIF4EBP1 (pS65) Antibody

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