EIF4EBP1 (pT36) Antibody

EIF4EBP1 (pT36) Antibody is a Rabbit Polyclonal antibody against EIF4EBP1 (pT36). This gene encodes one member of a family of translation repressor proteins. The protein directly interacts with eukaryotic translation initiation factor 4E (eIF4E), which is a limiting component of the multisubunit complex that recruits 40S ribosomal subunits to the 5' end of mRNAs. Interaction of this protein with eIF4E inhibits complex assembly and represses translation. This protein is phosphorylated in response to various signals including UV irradiation and insulin signaling, resulting in its dissociation from eIF4E and activation of mRNA translation.

Target	EIF4EBP1 (pT36)
Clonality	Polyclonal
Reactivity	Human, Mouse, Rat
Tested Applications	WB
Host	Rabbit
Recommended dilutions	WB: 1/500 - 1/2000, IHC 1/50 - 1/100. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	A synthetic phosphorylated peptide around T36 of human eIF4EBP1.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	Q13541 (UniProt, ExPASy)
UniProt Secondary AC	B2R502, D3DSW8, Q6IBN3
UniProt Entry Name	4EBP1_HUMAN
Gene Symbol	EIF4EBP1
GeneID	1978
NCBI Accession	NP_004086.1
KEGG	hsa:1978
String	9606.ENSP00000340691
Molecular Weight	Calculated MW: 13 kDa Observed MW: 20 kDa
Buffer	PBS, pH 7.3, containing 0.01% thimerosal, 50% glycerol.
Concentration	> 0.2 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on EIF4EBP1 (pT36)

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