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Eukaryotic Translation Initiation Factor 4 Gamma 1 (EIF4G1) Antibody

Catalogue No: abx000885
Price: £220.00
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EIF4G1 Antibody is a Rabbit Polyclonal antibody against EIF4G1. The protein encoded by this gene is a component of the multi-subunit protein complex EIF4F. This complex facilitates the recruitment of mRNA to the ribosome, which is a rate-limiting step during the initiation phase of protein synthesis. The recognition of the mRNA cap and the ATP-dependent unwinding of 5'-terminal secondary structure is catalyzed by factors in this complex. The subunit encoded by this gene is a large scaffolding protein that contains binding sites for other members of the EIF4F complex. A domain at its N-terminus can also interact with the poly(A)-binding protein, which may mediate the circularization of mRNA during translation. Alternative splicing results in multiple transcript variants, some of which are derived from alternative promoter usage.

Target EIF4G1
Clonality Polyclonal
Reactivity Human, Mouse, Rat
Tested Applications WB, IHC, IF/ICC, IP
Host Rabbit
Recommended dilutions WB: 1/500 - 1/1000, IHC: 1/50 - 1/100, IF/ICC: 1/20 - 1/50, IP: 1/20 - 1/50. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Recombinant fusion protein of human EIF4G1.
Isotype IgG
Form Liquid
Purification Affinity purified.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC Q04637 (UniProt, ExPASy)
UniProt Entry Name IF4G1_HUMAN
Gene Symbol EIF4G1
GeneID 1981
String 9606.ENSP00000416255
Molecular Weight Calculated MW: 154 kDa, 158 kDa, 166 kDa, 171 kDa, 175 kDa, 176 kDa
Observed MW: 175 kDa
Buffer PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
Concentration > 1 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on Eukaryotic Translation Initiation Factor 4 Gamma 1 (EIF4G1) Antibody

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