Eukaryotic Translation Initiation Factor 4 Gamma 1 (EIF4G1) Antibody

EIF4G1 Antibody is a Rabbit Polyclonal antibody against EIF4G1. The protein encoded by this gene is a component of the multi-subunit protein complex EIF4F. This complex facilitates the recruitment of mRNA to the ribosome, which is a rate-limiting step during the initiation phase of protein synthesis. The recognition of the mRNA cap and the ATP-dependent unwinding of 5'-terminal secondary structure is catalyzed by factors in this complex. The subunit encoded by this gene is a large scaffolding protein that contains binding sites for other members of the EIF4F complex. A domain at its N-terminus can also interact with the poly(A)-binding protein, which may mediate the circularization of mRNA during translation. Alternative splicing results in multiple transcript variants, some of which are derived from alternative promoter usage.

Target	Eukaryotic Translation Initiation Factor 4 Gamma 1 (EIF4G1)
Clonality	Polyclonal
Reactivity	Human
Tested Applications	WB
Host	Rabbit
Recommended dilutions	WB: 1/500 - 1/1000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	A synthetic peptide corresponding to a sequence within amino acids 550-650 of human EIF4G1.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	Q04637 (UniProt, ExPASy)
UniProt Entry Name	IF4G1_HUMAN
Gene Symbol	EIF4G1
GeneID	1981
NCBI Accession	NP_886553.3
KEGG	hsa:1981
String	9606.ENSP00000416255
Molecular Weight	Calculated MW: 175 kDa Observed MW: 250 kDa
Buffer	PBS, pH 7.3, containing 0.01% thimerosal, 50% glycerol.
Concentration	> 0.2 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Eukaryotic Translation Initiation Factor 4 Gamma 1 (EIF4G1)

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