Eukaryotic Translation Initiation Factor 4 Gamma 1 (EIF4G1) Antibody
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Catalogue No: abx000885
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US$217.50
(Size: 20 µl)
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Datasheet SDS
EIF4G1 Antibody is a Rabbit Polyclonal antibody against EIF4G1. The protein encoded by this gene is a component of the multi-subunit protein complex EIF4F. This complex facilitates the recruitment of mRNA to the ribosome, which is a rate-limiting step during the initiation phase of protein synthesis. The recognition of the mRNA cap and the ATP-dependent unwinding of 5'-terminal secondary structure is catalyzed by factors in this complex. The subunit encoded by this gene is a large scaffolding protein that contains binding sites for other members of the EIF4F complex. A domain at its N-terminus can also interact with the poly(A)-binding protein, which may mediate the circularization of mRNA during translation. Alternative splicing results in multiple transcript variants, some of which are derived from alternative promoter usage.
Research Articles on Eukaryotic Translation Initiation Factor 4 Gamma 1 (EIF4G1)
| Target | Eukaryotic Translation Initiation Factor 4 Gamma 1 (EIF4G1) |
| Research Area | Signal Transduction |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB |
| Host | Rabbit |
| Recommended dilutions | ELISA: 1 µg/ml, WB: 1/500 - 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Synthetic peptide corresponding to EIF4G1. The exact sequence is proprietary. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | Q04637 (UniProt, ExPASy) |
| UniProt Entry Name | IF4G1_HUMAN |
| Gene Symbol | EIF4G1 |
| GeneID | 1981 |
| OMIM | 600495 |
| NCBI Accession | NP_886553.3 |
| HGNC | 3296 |
| KEGG | hsa:1981 |
| Ensembl | ENSG00000114867 |
| String | 9606.ENSP00000416255 |
| Molecular Weight | Calculated MW: 175 kDa Observed MW: 250 kDa |
| Buffer | PBS, pH 7.3, containing 0.05% Proclin-300, 50% glycerol. |
| Concentration | > 0.2 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |