Eukaryotic Translation Initiation Factor 4 Gamma 2 (EIF4G2) Antibody

Catalogue No: abx002128
Price: £120.00
(Size: 20 µl)
Reviews: 0 reviews
(0 reviews)

Click on the image to see the image legend

Available Options

* Size:




EIF4G2 Antibody is a Rabbit Polyclonal antibody against EIF4G2. Translation initiation is mediated by specific recognition of the cap structure by eukaryotic translation initiation factor 4F (eIF4F), which is a cap binding protein complex that consists of three subunits: eIF4A, eIF4E and eIF4G. The protein encoded by this gene shares similarity with the C-terminal region of eIF4G that contains the binding sites for eIF4A and eIF3; eIF4G, in addition, contains a binding site for eIF4E at the N-terminus. Unlike eIF4G, which supports cap-dependent and independent translation, this gene product functions as a general repressor of translation by forming translationally inactive complexes. In vitro and in vivo studies indicate that translation of this mRNA initiates exclusively at a non-AUG (GUG) codon. Alternatively spliced transcript variants encoding different isoforms of this gene have been described.

Target EIF4G2
Clonality Polyclonal
Reactivity Human, Mouse, Rat
Tested Applications WB, IHC, IF/ICC, IP
Host Rabbit
Recommended dilutions WB: 1/500 - 1/1000, IHC: 1/100 - 1/200, IF/ICC: 1/50 - 1/200, IP: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen A synthetic peptide of human EIF4G2.
Isotype IgG
Form Liquid
Purification Purified by affinity chromatography.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC P78344 (UniProt, ExPASy)
UniProt Entry Name IF4G2_HUMAN
Gene Symbol EIF4G2
GeneID 1982
KEGG hsa:1982
String 9606.ENSP00000433664
Molecular Weight Calculated MW: 98 kDa, 102 kDa
Observed MW: 110 kDa
Buffer PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
Concentration > 0.5 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on EIF4G2

Write a review

Your Name
Your Email Address
PMID
DOI
Your Review

Note: HTML is not translated!

Rating Bad Good


Tags:
(Click to show)