Eukaryotic Translation Initiation Factor 4 Gamma 2 (EIF4G2) Antibody

Catalogue No: abx002128
Price: £120.00
(Size: 20 µl)
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Eukaryotic Translation Initiation Factor 4 Gamma 2 (EIF4G2) Antibody Eukaryotic Translation Initiation Factor 4 Gamma 2 (EIF4G2) Antibody Eukaryotic Translation Initiation Factor 4 Gamma 2 (EIF4G2) Antibody Eukaryotic Translation Initiation Factor 4 Gamma 2 (EIF4G2) Antibody Eukaryotic Translation Initiation Factor 4 Gamma 2 (EIF4G2) Antibody

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EIF4G2 Antibody is a Rabbit Polyclonal antibody against EIF4G2. Translation initiation is mediated by specific recognition of the cap structure by eukaryotic translation initiation factor 4F (eIF4F), which is a cap binding protein complex that consists of three subunits: eIF4A, eIF4E and eIF4G. The protein encoded by this gene shares similarity with the C-terminal region of eIF4G that contains the binding sites for eIF4A and eIF3; eIF4G, in addition, contains a binding site for eIF4E at the N-terminus. Unlike eIF4G, which supports cap-dependent and independent translation, this gene product functions as a general repressor of translation by forming translationally inactive complexes. In vitro and in vivo studies indicate that translation of this mRNA initiates exclusively at a non-AUG (GUG) codon. Alternatively spliced transcript variants encoding different isoforms of this gene have been described.

Target EIF4G2
Clonality Polyclonal
Reactivity Human, Mouse, Rat
Tested Applications WB, IHC
Host Rabbit
Recommended dilutions WB: 1/500 - 1/1000, IHC: 1/100 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen A synthetic peptide of human EIF4G2.
Isotype IgG
Form Liquid
Purification Affinity purified.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC P78344 (UniProt, ExPASy)
UniProt Entry Name IF4G2_HUMAN
Gene Symbol EIF4G2
GeneID 1982
KEGG hsa:1982
String 9606.ENSP00000433664
Molecular Weight Calculated MW: 98 kDa, 102 kDa
Observed MW: 110 kDa
Buffer PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
Concentration > 1 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on Eukaryotic Translation Initiation Factor 4 Gamma 2 (EIF4G2) Antibody

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